Clinical studies in the age of personalized medicine

Let us invite you to a workshop of the interactive platform PharmAround and the Masaryk Cancer Institute on the topic "Clinical studies in the time of personalized medicine", which takes place on Wednesday, April 27, 2016 in the afternoon as part of the 40th Brno Cancer Days conference.

Clinical studies are an integral part of medicine and have a tradition at the Masaryk Oncology Institute for two decades. In recent years, oncological studies have been carried out mainly in specialized centers and teaching hospitals, and their complexity is growing in all aspects. The number of early phase studies is also increasing, the course of which is entirely tied to the so-called Phase I Units and their trained team.

In the first part of the workshop we will focus on the statistical design of clinical trials, in the second part we would like to present the current challenges in the field of clinical trials at the national and regional level, including the possible benefits of cooperation between oncologists.

Program

14: 15-15: 30

block I: Good statistical practice in the design and interpretation of clinical trials (Svobodník A., Demlová R.)

Statistical design of oncological clinical studies in phases I-III. Correct "endpoints" with respect to the phase of the clinical study. The size of the evaluated group and possible impacts on the suitability of including patients in clinical trials in the time of personalized medicine. The most common errors in the interpretation and extrapolation of the conclusions of clinical trials into clinical practice (Svobodník A.).

16: 00-17: 45

block II: Clinical studies in the period of personalized medicine - benefits of cooperation between oncologists (Obermannová R., Demlová, R., Čečetková B.)

Current state of clinical trials in the Czech Republic - AIFP survey (Čečetková B.) Specifics of early phase clinical trials (Obermannová R.) The main difficulties in conducting clinical trials or without cooperation will not work (Demlová R.) Overview of ongoing clinical trials in breast cancer (Petráková K.) Overview of ongoing clinical studies in GIT tumors and in urooncology (Kiss I., Lakomý R.) Joint discussion - possibilities of improving information and mutual cooperation between oncologists

The Workshop fee is without registration fees.

Contact

Jan Vyletěl - vyletel@pharmaround.cz; +420 730 177 010